The present invention relates to a central blood pressure estimation device (11). The device comprises a cuff (12)； a signal record and storage unit (14) capturing a pressure oscillometric waveform from the cuff and storing the waveform； and an operation and analysis unit obtaining a set of values from the waveform, wherein the values includes a pressure value of the late systolic shoulder produced by wave reflections, an end-systolic pressure value, an area value under the waveform during systole, an area value under the waveform during diastole, a pressure value at end-diastole, and a value of heart rate, and respectively substituting the set of values for corresponding control variables in a linear regression equation to obtain a central blood pressure value, wherein the linear regression equation has a central blood pressure as a dependent variable and has a pressure of the late systolic shoulder produced by wave reflections, an end-systolic pressure, an area under the waveform during systole, an area under the waveform during diastole, a pressure at end-diastole, and a heart rate as the control variables.
