600566 Disclosed is an oil-in-water formulation for the inhibition of the transmission of sexually transmitted diseases, characterised by enhanced skin protective properties consisting of in combination: (1) a skin protectant composition selected from the group consisting of allantoin, aluminium hydroxide gel, calamine, cocoa butter, cod liver oil, colloidal oatmeal, hard fat, kaolin, mineral oil, petrolatum, topical starch, white petrolatum, zinc acetate, zinc carbonate, zinc oxide, and mixtures thereof, provided in a skin protecting effective concentration； (2) a silicone-based skin protectant composition containing at least one silicone-containing excipient (such as dimethicone 20 and / or dimethicone 12500) provided in a skin protecting effective concentration； (3) a humectant excipient, selected from the group consisting of glycerine, anhydrous lanolin and combinations thereof, in the range of about 0.5 to 15.0 % wt/wt； (4) a non-ionic emulsifier selected from the group consisting of cetearyl alcohol, ceteareth-12, ceteareth-20 and mixtures thereof, in the range from about 0.5 to 15.0 % wt/wt； (5) a chelating compound in the range from about 0.1 to 0.01 % wt/wt； (6) alkyltrimethylammonium bromide in the range from about 0.01 to 0.25 % wt/wt； (7) a film-forming emollient (such as cetostearyl alcohol and / or cetyl alcohol) in the range from about 1.0 to 10.0% wt/wt； and (8) water； wherein contact with the skin results in the in situ formation of a skin protective barrier layer effective in preventing transmission of sexually transmitted diseases.
