Erik Torbjörn Lundstedt;Jon Robert Gabrielsson;Nils Johan Trygg;Gunilla Ekström
发明人:
Erik Torbjörn Lundstedt,Nils Johan Trygg,Jon Robert Gabrielsson,Gunilla Ekström
申请号：
US13259733
公开号：
US20120108668A1
申请日:
2010.03.24
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to the use of endogenous metabolites to produce a metabolic profile of a disorder or disease in a subject, e.g. an autoimmune disease, in particular rheumatoid arthritis, and the analysis of such metabolic profiles in order to find disturbances in such profiles in a subject which are caused by or correlated with the said diseases or disorders. Such disturbances can be normalised by treatment of the subject with specified compounds, particularly N-(2-chloro-3,4-dimethoxybenzylideneamino)guanidine or an aminoguanidine.
