The present invention relates to an addition agent used for bone cement comprises cross-linked poly (methyl methacrylate-acrylic acid sodium salt -allylmethacrylate). The present invention also relates to a bone cement comprises said addition agent, main agent and at least one medicine, and the bone cement provide higher medical release rates. The bone cement with higher medical release rates by regulating the volume ratio of methyl methacrylate, acrylic acid sodium salt and allylmethacrylate of the addition agent could reduce the infection in surgical transplantation.本發明提供一種用於骨水泥之添加劑,其包含聚合交聯聚(甲基丙烯酸甲酯-丙烯酸鈉鹽-甲基丙烯酸烯丙酯)[cross-linked poly(methyl methacrylate-acrylic acid sodium salt-allylmethacrylate),cross-linked poly(MMA-AAS-AMA)];本發明更提供一種骨水泥,其包含前述骨水泥添加劑、主劑以及至少一藥物,該骨水泥具有較高的藥物釋放速率。本發明之骨水泥係藉由調控添加劑之甲基丙烯酸甲酯、丙烯酸鈉鹽以及甲基丙烯酸烯丙酯的體積比例,以提高骨水泥的藥物釋放速率,並可降低外科移植感染之風險。
