PROBLEM TO BE SOLVED: To provide an emulsion in which a physiologically acceptable salt of tranexamic acid ester with a low solubility to water and oil is dispersed into a composition in a stable condition.SOLUTION: The invention provides an emulsion in which an oil phase is dispersed into an external phase having a both continuing structure. The external phase comprises: A) physiologically acceptable salt of tranexamic acid ester B) an amphiphilic agent selected from combinations of a straight chain or branched chain saturated or unsaturated alcohol of a carbon number of 12-22, and an alkyl glyceryl ether which is mono- or di-ether of a straight chain or branched chain saturated or unsaturated alcohol with a carbon number of 8-22 and glycerin C) oil solution and D) water. The oil phase which is a dispersion phase contains E) an oil solution. The total content of the component which constitutes the external phase to the total mass of the emulsion is 55-95 mass%. The total content of the component which constitutes the dispersion phase is 5-45 mass%.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2016,JPO&INPIT【課題】水及び油に対する溶解度が低いトラネキサム酸エステルの生理学的に許容される塩を組成物中に安定な状態で分散させてなるエマルションの提供。【解決手段】両連続構造を有する外相中に油相が分散されてなるエマルションであって、外相が、A)トラネキサム酸エステルの生理学的に許容される塩;B)炭素数12~22を有する直鎖又は分岐鎖の飽和又は不飽和のアルコール、及び、炭素数8~22を有する直鎖又は分岐鎖の飽和又は不飽和のアルコールとグリセリンとのモノ又はジエーテルであるアルキルグリセリルエーテルの組み合わせから選ばれる両親媒性物質;C)油剤;及びD)水を含み、分散相である油相がE)油剤を含み、エマルションの全質量に対して、外相を構成する成分の含有量の合計が55~95質量%であり、分散相を構成する成分の含有量の合計が5~45質量%であるエマルション。【選択図】図1
