The invention provides a topical o/w emulsion which moisturizes, and protects, repairs or restores the skin lipid barrier of a mammal. The topical o/w emulsion composition comprises: (a) a discontinuous oil phase； (b) a continuous aqueous phase comprising water； (c) a thickening agent； (d) at least one lamellar membrane structure comprising (i) a phospholipid, (ii) a fatty alcohol, and (iii) a fatty acid； and wherein in use the composition has a water vapor transmission rate of less than about 70 g.m-2.hr-1 measured in vitro using the modWVTR test methodology.本發明係提供局部o/w乳液，其可潤濕，及保護，修復或恢復哺乳類的皮膚脂質屏障。該局部o/w乳液組成物包括：(a)不連續油相；(b)包括水之連續水相；(c)增稠劑；(d)至少一個層狀膜結構，其包括(i)磷脂，(ii)脂肪醇，及(iii)脂肪酸；及當使用時，該組成物之水氣傳輸率以modWVTR測試方法體外測量係少於約70g.m-2.hr-1。
