Pallav Arvind BULSARA,Martyn J. Clarke,Dara Lisa Dinner,Alireza Shalviri
申请号:
US15916360
公开号:
US20180303731A1
申请日:
2018.03.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides a topical o/w emulsion which moisturizes, and protects, repairs or restores the skin lipid barrier of a mammal. The topical o/w emulsion composition comprises:a) a discontinuous oil phaseb) a continuous aqueous phase comprising waterc) a thickening agentd) at least one lamellar membrane structure comprising (i) a phospholipid, (ii) a fatty alcohol, and (iii) a fatty acide) a pharmaceutically acceptable active agent andf) optionally a dermatologically acceptable excipient.In one embodiment, the composition, in use, has a water vapor transmission rate of less than or about 75 g·m−2·hr−1 measured in vitro using the modWVTR test methodology.