The invention relates generally to multispecific polypeptides having dual effector functions, as well as to methods of making and using these multispecific polypeptides in a variety of therapeutic, diagnostic and prophylactic indications.本發明概言之係關於具有雙重效應物功能之多重特異性多肽以及製備該等多重特異性多肽之方法及使用該等多重特異性多肽於多種治療性、診斷性及預防性適應症之方法。