PROBLEM TO BE SOLVED: To provide a pharmaceutical composition comprising chili pepper or an extract thereof and having excellent storage stability, as well as agents for stabilizing storage property of the pharmaceutical composition and methods for stabilizing the pharmaceutical composition.SOLUTION: The pharmaceutical composition of the invention comprises: (A) one or more kinds of chili pepper (fruits of Capsicum annuum Linne (Solanaceae)) and extracts thereof； (B) loxoprofen or a salt thereof； (C) one or more ingredients selected from the group consisting of the following (C-1) and (C-2) compounds, where (C-1) is a compound represented by the formula (1) or a salt thereof [X is a single bond or O； Y is a methine group or N； Ris H, a hydroxyl group or alkyl group； Ris a substituted/unsubstituted cyclic amino group or a substituted/unsubstituted aminoalkyl group； Ris H or a halogen atom], and (C-2) is a polyalcohol.【課題】トウガラシやその抽出物を含有し、優れた保存安定性を有する医薬組成物、並びに該医薬組成物の保存安定化剤及び安定化方法。【解決手段】（Ａ）トウガラシ及びその抽出物から選ばれる１種以上、（Ｂ）ロキソプロフェン又はその塩、（Ｃ）次の成分（Ｃ－１）及び（Ｃ－２）からなる群より選ばれる１種以上を含有する医薬組成物。（Ｃ－１）式（１）で表される化合物又はその塩［Ｘは単結合又はＯ；Ｙはメチン基又はＮ；Ｒ1はＨ、水酸基又はアルキル基；Ｒ2は置換基／非置換の環状アミノ基又は置換基／非置換のアミノアルキル基；Ｒ3はＨ又はハロゲン原子]（Ｃ－２）多価アルコール、【選択図】なし
