JULIUSZ PERNAK,PERNAK JULIUSZ,ANDRZEJ SKRZYPCZAK,SKRZYPCZAK ANDRZEJ
申请号：
PL397794
公开号：
PL218152B1
申请日:
2012.01.13
申请国别(地区):
PL
年份:
2014
代理人:
摘要：
described dichlorooctany dimethylammonium ion liquids zwalczajace anti - cancer cells and receive dichlorooctan\u00f3w dimetyloamoniowych,for use in a pharmaceutical.antineoplastic dichlorooctany dimethylammonium ion starring as liquids of the general formula (2), in which r1 is a alkilowa containing from 1 to 16 carbon atoms.and r2 is the group alkilowa containing from 1 to 16 carbon atoms or a benzylowa or group alkoksymetylowa ch2or3,in which r3 means a alkilowa containing from 1 to 16 carbon atoms or a ch2o (ch2) noch2n + (ch3) 2r4,in which r4 means a alkilowa containing from 1 to 16 carbon atoms and n is a value of from 1 to 12.the way they receive is, in the environment with organic solvent or water, chlorides or bromides or iodides give up or hydroxides dimethylammonium of general formula 1,where r2 is a alkilowa containing from 1 to 16 carbon atoms and r2 is a group alkilowa containing from 1 to 16 carbon atoms or a benzylowa or group alkoksymetylowa ch2or3,in which r3 means a alkilowa containing from 1 to 16 carbon atoms or a ch2o (ch2) noch2n + (ch3) 2r4,in which r4 means a alkilowa containing from 1 to 16 carbon atoms and n is a value of from 1 to 14, - ion exchange reaction needed to exchange chlorkowego nitrate, or bromkowego,or jodkowego or wodorotlenkowego on anion dichlorooctowy, using dichlorooctanu lithium, potassium or sodium dichlorooctanu, dichlorooctanu acid dichlorooctowego.then oddestylowujes organic solvent or water.be also separates out water through chapter phases and after oddestylowaniu solvent and drying pozostalosc dissolves in organic solvent at temp.276 - 400 k, and then with mixtures in known manner is to salt.Opisano przeciwnowotworowe dichlorooctany dimetyloamoniowe - ciecze jonowe zwalczajace komórki nowotworowe oraz sposób otrzymywania dichlorooctanów dimetyloamoniowych, do zastosowania w przemysle farmaceutycznym. Przeciwnowotworowe dichlorooctany dimetyloamoniowe wystepuja jako ciecze jonowe o ogólnym wzorze 2, w którym R1 ozn
