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Bioinformatically detectable group of novel regulatory genes and uses thereof
专利权人:
Itzhak Bentwich
发明人:
Itzhak Bentwich
申请号:
US10707147
公开号:
US08163896B1
申请日:
2003.11.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a first group of novel genes, here identified as genomic address messenger or GAM genes, and a second group of novel operon-like genes, here identified as genomic record or GR genes. GAM genes selectively inhibit translation of known ‘target’ genes, many of which are known to be involved in various diseases. Nucleic acid molecules are provided respectively encoding 200 GAM genes, and 1096 GR genes, as are vectors and probes both comprising the nucleic acid molecules, and methods and systems for detecting GAM and GR genes and specific functions and utilities thereof, for detecting expression of GAM and GR genes, and for selectively enhancing and selectively inhibiting translation of the respective target genes thereof.
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