The invention relates to a sterilizable biopharmaceutical packaging (1) capable of containing biopharmaceutical contents to be sterilized. Specifically, the packaging according to the invention comprises an opening (6) for inserting the biopharmaceutical contents to be sterilized, said opening being separate from tHe sterilization gas conveyance channel (7) so that the opening (6) for inserting the biopharmaceutical contents to be sterilized can be closed independently and before closing the sterilization gas conveyance channel (7). Additionally, the opening (6) for inserting the biopharmaceutical contents to be sterilized is di!ectly adjacent to the inner space (2) for receiving the biopharmaceutical contents to be sterilized and the sterilized biopharmaceutical contents so that the biopharmaceutical contents to be sterilized are inserted directly into the inner space (2) from outside the packaging (1). The means (12) for controlling the distribution of the sterilization gas is a means (12) for opening/closing the sterilization gas conveyance channel (7) so that the sterilization gas conveyance channel (7) can be opened or closed independently of the opening or closing of the insertion opening (6). Once the sterilization is performed, the outer wall (3), the sterilization gas conveyance channel (7), and the opening/closing means (12) are capable ofremaining rigidly connected therebetween so as to form a sterilized biopharmaceutical packaging (1) that contains the sterilized biopharmaceutical contents and dm be subjected to one or more integrity tests at any desired time after the sterilization