Various types of low level laser therapy (LLLT) wrap devices, methods of use, and a system comprising a mobile application, for the treatment of pain from musculoskeletal injuries or medical conditions, and to capture “patient's vitals”. Each wrap is fitted to a specific body part (e.g. knee), lightweight, portable so that it is wearable beneath clothing; and with a battery-powered electrical circuit embedded within the wrap, comprising: a plurality of laser diodes to treat surface and/or deep tissue pain; sensors (e.g. safety and/or patient vital sign monitoring); and a wireless transceiver for transmitting data (sensor and patient pain levels) to a mobile application. The wrap may also function as an orthopedic support; and is pre-calibrated for a specific duration to deliver a clinical strength dosage from 630 nm to 904 nm that is specific to the medical disorder and/or the user anatomical area, with an automatic shut-off after dose delivery.