Toby Jonathan Blench,Charles Ellwood,Simon Charles Goodacre,Yingjie Lai,Jun Liang,Calum MacLeod,Steven R. Magnuson,Vickie Hsiao-Wei Tsui,Karen Williams,Birong Zhang
申请号:
US14185700
公开号:
US20140171408A1
申请日:
2014.02.20
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided are compounds of Formula I, stereoisomers, tautomers, solvates, prodrugs and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, methods of using the compound or composition in therapy, and methods of manufacturing a compound of Formula I.