Toby Jonathan Blench,Charles Ellwood,Simon Charles Goodacre,Yingjie Lai,Jun Liang,Calum Macleod,Steven R. Magnuson,Vickie H. Tsui,Karen Williams,Birong Zhang
申请号：
US13232778
公开号：
US08697708B2
申请日:
2011.09.14
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Provided are compounds of Formula I, stereoisomers, tautomers, solvates, prodrugs and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, methods of using the compound or composition in therapy, and methods of manufacturing a compound of Formula I.
