Michael Eissenstat,Dehui Duan,Sergi Gulnik,John W. Erickson
申请号:
US12919012
公开号:
US08952056B2
申请日:
2009.02.23
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Methods of inhibiting cytochrome P450 enzymes are provided that can be used for improving the treatment of diseases by preventing degradation of drugs or other molecules by cytochrome P450. Pharmaceutical compositions are provided that can act as boosters to improve the pharmacokinetics, enhance the bioavailability, and enhance the therapeutic effect of drugs that undergo in vivo degradation by cytochrome P450 enzymes.