Koji Kadowaki,Akihiro Saito,Megumi Nakanishi,Masaki Fujita,Kazuhiro Tanahashi
申请号：
US15577027
公开号：
US20180140752A1
申请日:
2016.05.27
申请国别(地区):
US
年份:
2018
代理人:
摘要：
An antithrombogenic material includes a coating material containing: a cationic polymer containing, as a constituent monomer, a compound selected from the group consisting of alkyleneimines, vinylamines, allylamines, lysine, protamine, and diallyldimethylammonium chloride； and an anionic compound containing a sulfur atom and having anticoagulant activity； and a base material whose surface is coated with the coating material； wherein the cationic polymer is covalently bound to the base material； the anionic compound containing a sulfur atom and having anticoagulant activity is immobilized on the surface of the base material by ionic bonding to the cationic polymer； and the average thickness of the coating material is 15 to 400 nm.
