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Gastric release pulse system for drug delivery
专利权人:
Henry H. Flanner;Sanna Tolle-Sander;Scott Ibrahim;Beth A. Burnside;Donald Treacy;Marcus Schestopol
发明人:
Henry H. Flanner,Donald Treacy,Sanna Tolle-Sander,Scott Ibrahim,Marcus Schestopol,Beth A. Burnside
申请号:
US11644707
公开号:
US09125803B2
申请日:
2006.12.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are pharmaceutical products for providing pulses of at least one pharmaceutically active ingredient from a patient's stomach, or from a subsequent gastrointestinal site proximal thereto, for absorption thereof at a site(s) more distal in the gastrointestinal tract than the patient's stomach, or than the subsequent gastrointestinal site proximal thereto. The product comprises first, second, and third pharmaceutical dosage forms, each of which comprises at least one pharmaceutically active agent and a pharmaceutically acceptable carrier. The product is formulated such that at least two of the first, second, and third pharmaceutical dosage forms further comprise means for providing temporary gastric-retention of the at least two of the first, second, and third pharmaceutical dosage forms within the patient's stomach, or at the subsequent gastrointestinal site proximal thereto.
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