BOTELLA, Gabriel Martinez,HARRISON, Boyd L.,ROBICHAUD, Albert Jean,SALITURO, Francesco G.,BERESIS, Richard Thomas
申请号:
DK15862506
公开号:
DK3224269T3
申请日:
2015.11.27
申请国别(地区):
DK
年份:
2020
代理人:
摘要:
Described herein are neuroactive steroids of the Formula (II) : or a pharmaceutically acceptable salt thereof; wherein A, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5, R6 and <;u>;-----<;/u>; are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e. g., such for inducing sedation and/or anesthesia.