Gabriel Martinez Botella,Francesco G. Salituro,Albert Jean Robichaud,Boyd L. Harrison
申请号:
US16365123
公开号:
US20200024301A1
申请日:
2019.03.26
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Described herein are neuroactive steroids of the Formula (I); or a pharmaceutically acceptable salt thereof, wherein, R1, R2a, R2b, R3 and A are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.