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COCRISTAUX DE COMPOSES DE BENZIMIDAZOLE
专利权人:
FAES FARMA; S.A.
发明人:
HERNANDEZ HERRERO, GONZALO,RUBIO ROYO, VICTOR,GARCIA DOMINGUEZ, NEFTALI,CANAL MORI, GONZALO,TESSON, NICOLAS,JIMENEZ GONZALEZ, CARME,DE MIER VINUE, JORDI
申请号:
CA3005387
公开号:
CA3005387A1
申请日:
2016.11.18
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to a cocrystal comprising a) at least bilastine and, b) at least a cocrystal forming compound selected from the group consisting of glutaric acid, adipic acid, sorbic acid, succinic acid, benzoic acid, 4-aminobenzoic acid, L-malic acid, resorcinol, methyl 4-hydroxy benzoate and N-(4- hydroxyphenyl)acetamide and mixtures thereof, or a solvate thereof. The invention further relates to methods for obtaining said cocrystals and to their use in the treatment and/or prevention of conditions mediated by H1 histamine receptor, such as allergic disorders or diseases. The invention also relates to a method for increase the aqueous solubility of the above compounds of formula (I).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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