HILL, RONALD STEWART,KLANN, RICHARD CHRIS,LAMBERTI, FRANCIS V.
申请号：
CA2543255
公开号：
CA2543255C
申请日:
2004.10.22
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Connective tissue regenerative compositions and methods of repairing andregenerating connective tissue using suchcompositions are provided. The compositions generally comprise a bioactivehydrogel matrix comprising a polypeptide, such asgelatin, and a long chain carbohydrate, such as dextran. The hydrogel matrixmay further include polar amino acids, as well asadditional beneficial additives. Advantageously, the compositions includefurther components, such as osteoinductive or osteocon-ductivematerials, medicaments, stem or progenitor cells, and three-dimensionalstructural frameworks. The compositions are usefulfor regenerating connective tissue, and can be administered to an area havinginjury to, or a loss of, connective tissue, such as bone,cartilage, tendon, and ligament.
