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PURINE DIONES UTILISEES COMME MODULATEURS DE LA VOIE WNT
专利权人:
AGENCY FOR SCIENCE; TECHNOLOGY AND RESEARCH
发明人:
HO, SOO YEI,BLANCHARD, STEPHANIE ELIANE,DURAISWAMY, ATHISAYAMANI JEYARAJ,ALAM, JENEFER,ADSOOL, VIKRANT ARUN
申请号:
CA2912757
公开号:
CA2912757A1
申请日:
2014.05.19
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The invention relates to the use of compounds of general structure (I) in modulation of the Wnt pathway [Formula should be inserted here] wherein R1, R2, R3, R4 and R5 are each, independently, H or an alkyl group; D is selected from the group consisting of H, halogen, alkyl, cycloalkyl, aryl, and dialkylamino, each (other than H and halogen) being optionally substituted; Ar is an aryl or heteroaryl group, optionally substituted; Cy is an aryl, heteroaryl or a saturated ring containing at least one heteroatom, each being optionally substituted; and n is an integer from 1 to 3.
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