Soo Yei Ho,Stephanie Eliane Blanchard,Athisayamani Jeyaraj Duraiswamy,Jenefer Alam,Vikrant Arun Adsool
申请号：
US14893172
公开号：
US09926320B2
申请日:
2014.05.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to the use of compounds of general structure (I) in modulation of the Wnt pathway [Formula should be inserted here] wherein R1, R2, R3, R4 and R5 are each, independently, H or an alkyl group； D is selected from the group consisting of H, halogen, alkyl, cycloalkyl, aryl, and dialkylamino, each (other than H and halogen) being optionally substituted； Ar is an aryl or heteroaryl group, optionally substituted； Cy is an aryl, heteroaryl or a saturated ring containing at least one heteroatom, each being optionally substituted； and n is an integer from 1 to 3.
