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PURINE DIONES AS WNT PATHWAY MODULATORS
专利权人:
Agency for Science; Technology and Research
发明人:
Soo Yei HO,Stephanie Eliane BLANCHARD,Athisayamani Jeyaraj DURAISWAMY,Jenefer ALAM,Vikrant Arun ADSOOL
申请号:
US16716268
公开号:
US20200190086A1
申请日:
2019.12.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to the use of compounds of general structure (I) in modulation of the Wnt pathway [Formula should be inserted here] wherein R1, R2, R3, R4 and R5 are each, independently, H or an alkyl group; D is selected from the group consisting of H, halogen, alkyl, cycloalkyl, aryl, and dialkylamino, each (other than H and halogen) being optionally substituted; Ar is an aryl or heteroaryl group, optionally substituted; Cy is an aryl, heteroaryl or a saturated ring containing at least one heteroatom, each being optionally substituted; and n is an integer from 1 to 3.
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