CIBLAGE DE CELLULES SOUCHES CANCÉREUSES HYPOXIQUES (CSC) À L'AIDE DE DOXYCYCLINE : IMPLICATIONS POUR AMÉLIORER UNE THÉRAPIE ANTI-ANGIOGÉNIQUE

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专利权人:

Lunella Biotech; Inc.

发明人:

申请号：

EP18787729.5

公开号：

EP3612177A1

申请日:

2018.04.20

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present disclosure relates to inhibitors of mitochondrial function. Methods of treating hypoxic cancer cells using anti-angiogenic agents and mitochondrial biogenesis inhibitors are disclosed. Tetracyclines, such as doxycycline, may serve as mitochondrial biogenesis inhibitors. Also described are methods of sensitizing hypoxic cancer cells to one or more chemotherapies by administering a mitochondrial biogenesis inhibitor with the chemotherapy.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/