肯塔基大學研究基金會;代表亞利桑那大學的亞利桑那校董會;UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION;ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSI
发明人:
JACOBSON, Elaine, L. L,JACOBSON, Myron, K. K,COYLE, Russell,KIM, Hyuntae,COYLE, Donna, L. L,休達‧基姆,唐娜‧,‧科伊爾,伊萊恩‧,‧雅各布森,邁倫‧,拉塞爾‧科伊爾
申请号：
HK10110556.3
公开号：
HK1143955B
申请日:
2010.11.12
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The invention relates to the use of nicotinic acid alkyl esters, especially myristyl nicotinate, to inhibit side effects associated with retinoic acid therapy. Also a part of the invention is a method for improving skin cell differentiation by administering the nicotinic acid alkyl ester in an amount sufficient to increase expression of caspase 14 and filaggrin. Deficiencies in expression of these molecules can be treated in this way as well.
