Disclosed herein are valves, such as an aortic valve replacement can be delivered via a transcatheter approach can be deployed by a single operator through a lower profile (e.g., 8-12 French, or even less) delivery system. Lower profile delivery systems can advantageously potentially expedite procedures and reduce complications, as they tend to be easier to navigate through the vascular anatomy. In some embodiments, the valve system can be deployed in a multiple stage approach as two separate components, rather than a single unified component first a stent, followed by a discrete structure such as a valve support that includes the valve leaflets. The components can be positioned separately during delivery at different locations in and over the catheter. The stent can include a pair of rows of hooks directed in directions opposite to one another. The valve support can include struts having retaining structures that form a spherical configuration when retained together by a grasping member to keep the valve folded and conical during delivery thereof inside the catheter.