TOLERIZATION REDUCES INTOLERANCE TO PEGLOTICASE AND PROLONGS THE URATE LOWERING EFFECT (TRIPLE)

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专利权人:

Horizon Pharma Rheumatology LLC

发明人:

Jeffrey D. KENT,Brian LAMOREAUX

申请号：

US16777625

公开号：

US20200237879A1

申请日:

2020.01.30

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The disclosure provides methods of treating gout in patients comprising administering a PEGylated uricase. Also provided are methods of treating gout in patients comprising co-administering a PEGylated uricase and azathioprine immunosuppressive therapy. Also provided are methods of reducing intolerance or enhancing immuno-tolerance to a PEGylated uricase and prolonging the urate lowering effect comprising co-administration of the PEGylated uricase and azathioprine immunosuppressive therapy.

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中国工程科技知识中心

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http://www.ckcest.cn/home/