John BOTSON;Jeff PETERSON;Horizon Pharma Rheumatology LLC
发明人:
Jeffrey D. KENT,Brian LAMOREAUX,John BOTSON,Jeff PETERSON
申请号：
US16777646
公开号：
US20200237881A1
申请日:
2020.01.30
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The disclosure provides methods of treating gout in patients comprising administering a PEGylated uricase. Also provided are methods of treating gout in patients comprising co-administering a PEGylated uricase and methotrexate (MTX). Also provided are methods of reducing immunogenicity of a PEGylated uricase and prolonging the urate lowering effect comprising co-administration of the PEGylated uricase and MTX.
