PROBLEM TO BE SOLVED: To provide a skin barrier function recovering agent and a method for screening the same, and a method for recovering the skin barrier function using the same.SOLUTION: There are provided a method for screening the skin barrier function recovering agent with activation of TRPM8, which is one of thermosensitive receptors generally called a transient receptor potential (TRP) family, as a marker and a skin barrier function recovering agent containing a TRPM8 agonist.COPYRIGHT: (C)2012,JPO&INPIT【課題】皮膚バリア機能回復剤とそのスクリーニング方法、及びそれを利用した皮膚バリア機能回復方法の提供。【解決手段】一過性受容体電位(TRP)ファミリーと総称される幾つかの熱感受性レセプターの一つ、TRPM8の活性化を指標とする、皮膚バリア機能回復剤のスクリーニング方法、及びTRPM8アゴニストを含有する皮膚バリア機能回復剤。【選択図】なし
