<;P>;PROBLEM TO BE SOLVED: To develop a new application of &beta;-1,3-1,6-D-glucan. <;P>;SOLUTION: The subject enteric canal immune-activating agent, a proliferation-inducing agent of lymphocytes in an enteric canal-related lymphoid tissue, an agent for inducing the production of a cytokine in the enteric canal-related lymphoid tissue, an agent for inducing the production of IgA and an agent for preventing an infectious disease contain the &beta;-1,3-1,6-D-glucan. <;P>;COPYRIGHT: (C)2006,JPO&NCIPI