A double-chamber infusion bag, comprising a sealed soft infusion bag body (1). A first chamber (11) and a second chamber (12) are formed in the soft infusion bag body (1) via a first strip-shaped strippable cold joint structure (13). A second strip-shaped strippable cold joint structure (14) is disposed between the second chamber (12) and an opening tube (2). The breakthrough pressure of the second strip-shaped strippable cold joint structure (14) is greater than or equal to that of the first strip-shaped strippable cold joint structure (13). A composite aluminum film (17) or a transparent or semi-transparent composite material is fixedly connected to the outer side of the second chamber (12). A method for producing a double-chamber infusion bag comprises: manufacturing a double-chamber infusion bag body with an opening tube (2) by welding; filling a first chamber (11) with a liquid drug (15), and then sealing an opening; cutting an opening at the side edge of a second chamber (12) of the sterilized and dried double-chamber infusion bag body, filling with a powdery drug (16), and then sealing an opening; and finally, welding a composite aluminum film (17) or a transparent or semi-transparent composite material on the outer side face of the second chamber (12). It is ensured that a powdery drug (16) and a liquid drug (15) are fully mixed.L'invention concerne un sac de perfusion à double chambre, comprenant un corps de sac de perfusion souple étanche (1). Une première chambre (11) et une seconde chambre (12) sont formées dans le corps du sac à perfusion souple (1) par l'intermédiaire d'une première structure de joint (13) pelable à froid en forme de bande. Une seconde structure de joint pelable à froid en forme de bande (14) est disposée entre la seconde chambre (12) et un tube d'ouverture (2). La pression de fuite de la seconde structure de joint pelable à froid en forme de bande (14) est supérieure ou égale à celle de la première structure de joint pelable à froid (