NATCO PHARMA LIMITED;KOMPELLA, AMALA KISHAN;RACHAKONDA, SREENIVAS;ADIBHATLA KALI SATYA, BHUJANGA RAO;VENKAIAH CHOWDARY, NANNAPANENI;PODILI, KHADGAPATHI
发明人:
KOMPELLA, AMALA KISHAN,ADIBHATLA KALI SATYA, BHUJANGA RAO,RACHAKONDA, SREENIVAS,PODILI, KHADGAPATHI,VENKAIAH CHOWDARY, NANNAPANENI
申请号：
CA2591321
公开号：
CA2591321C
申请日:
2005.07.19
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to novel intermediates useful for the preparation of novel phenylaminopyrimidine derivatives, novel phenylaminopyrimidine derivatives. Pharmaceutical composition containing the novel phenylaminopyrimidine derivatives and processes for their preparation. The invention particularly relates to novel Phenyl pyrimidine amine derivatives of the general formula (I). The novel compounds of the formula 1 can be used in the therapy of Chronic Myeloid Leukemia (CML). Since the IC50； 191 values of these molecules are in the range 0.1 to 10.0 nm, these novel compounds are potentially useful for the treatment of CML.
