Imidazopiridazinas derivatives substituted with amino Compounds, inhibitors of the kinase, mknk2； Preparation method； Intermediate compounds and their pharmaceutical use； Pharmaceutical composition； Combination； and its use for the treatment of cancer.
The present invention relates to amino-substituted imidazopyridazine compounds of general formula (I): in which A, R1, R3 and n are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.Compuestos derivados de O-imidazopiridazina sustituida con benzofurano, inhibidor de quinasa MKNK1； compuesto intermediario； método de preparación, composición y combinación farmacéutica que los comprende； y su uso en el tratamiento del cáncer
