The Board of Regents of the University of Texas System
发明人:
Daniel J. Siegwart,Jason B. Miller
申请号:
US15597049
公开号:
US20170349543A1
申请日:
2017.05.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure provides one or more amino lipids such as an amino lipids containing a sulfonic acid or sulfonic acid derivative of the formulas:wherein the variables are as defined herein. These amino lipids may be used in compositions with one or more helper lipids and a nucleic acid therapeutic agent. These compositions may be used to treat a disease or disorder such as cancer, cystic fibrosis, or other genetic diseases.