The Board of Regents of the University of Texas System
发明人:
Daniel J. SIEGWART,Jason B. MILLER
申请号:
US16744118
公开号:
US20200140378A1
申请日:
2020.01.15
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure provides one or more amino lipids such as an amino lipids containing a sulfonic acid or sulfonic acid derivative of the formulas:wherein the variables are as defined herein. These amino lipids may be used in compositions with one or more helper lipids and a nucleic acid therapeutic agent. These compositions may be used to treat a disease or disorder such as cancer, cystic fibrosis, or other genetic diseases.