A sterilization system with integrated instrument recall capabilities andrelated methods is disclosed. In one aspect, the sterilization system isadapted todetermine a failed sterilization cycle of a sterilizer in response to failureof abiological indicator test for the sterilizer, identify sterilization cycles tobe recalledbased on the failed sterilization cycle, identify one or more patients forwhom anitem in a recalled sterilization cycle was used, and initiate a patientnotificationroutine comprising at least one of outputting of identifying information ofthe one ormore patients for whom an item in the recalled sterilization cycle was usedandnotifying the one or more patients for whom an item in the recalledsterilizationcycle was used about the recalled sterilization cycle.