Bourne, Gregory,Bhandari, Ashok,Cheng, Xiaoli,Frederick, Brian Troy,Zhang, Jie,Patel, Dinesh V.,Liu, David
申请号：
AU2015289642
公开号：
AU2015289642A1
申请日:
2015.07.15
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The present invention provides novel peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel disease. In a first aspect, the present invention provides a peptide inhibitor of an interleukin-23 receptor, or a pharmaceutically acceptable salt or solvate thereof, wherein the peptide inhibitor comprises an amino acid sequence of Formula (Xa). In another aspect, the present invention includes a pharmaceutical composition comprising a peptide inhibitor or a peptide dimer inhibitor of the present invention, and a pharmaceutically acceptable carrier.
