BOURNE GREGORY,BHANDARI ASHOK,CHENG XIAOLI,FREDERICK BRIAN TROY,ZHANG JIE,PATEL DINESH V,LIU DAVID
申请号：
IN201717002211
公开号：
IN201717002211A
申请日:
2017.01.20
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
The present invention provides novel peptide inhibitors of the interleukin 23 receptor and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders including inflammatory bowel disease. In a first aspect the present invention provides a peptide inhibitor of an interleukin 23 receptor or a pharmaceutically acceptable salt or solvate thereof wherein the peptide inhibitor comprises an amino acid sequence of Formula (Xa). In another aspect the present invention includes a pharmaceutical composition comprising a peptide inhibitor or a peptide dimer inhibitor of the present invention and a pharmaceutically acceptable carrier.
