RUI JIN HOSPITAL; SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE
发明人:
LU, MIN,WU, JIALE,SONG, HUAXIN
申请号:
CA3087461
公开号:
CA3087461A1
申请日:
2018.04.28
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Disclosed herein is a novel p53 complex and a collection of compounds that can tightly associate with p53 to efficiently rescue wildtype p53 structure and function, and the methods of making and using the complex and the compounds, including for diagnosis, prognosis, and treatment of p53 related disorders such as cancer and aging.