IN YOUNG CHOI,SE CHANG KWON,MYUNG HYUN JANG,SANG HYUN LEE,SUNG YOUB JUNG,JIN-SUN KIM
申请号：
ARP130102654
公开号：
AR091903A1
申请日:
2013.07.24
申请国别(地区):
AR
年份:
2015
代理人:
摘要：
Ingredients for the prevention or treatment of hyperlipidemia, fatty liver, or atherosclerosis include an oxygen modulated derivative as an active ingredient. Oxypolybrominated diphenyl ether derivatives have a strong ability to activate GLP-1 receptor and glucose receptor, which can reduce the content of blood cholesterol, low-density cholesterol and triglyceride, which increase with the diet with high fat content, and increase the content of high-density cholesterol. The relationship between high-density cholesterol and low-density cholesterol Therefore,Oxyglucose derivatives can be used in the treatment of hyperlipidemia and related diseases. 3. Characteristic 3: an ingredient in accordance with characteristic 1, characterized in that the oxygen degree modulation derivative is a variable formula combining the ingredients selected from the group, which is composed of immunoglobulin, antibody, elasticity, albumin or cellulose. Requirement 4: according to the composition of requirement 3,The characteristic of the copolymer is that the copolymer includes an oxygen modulated derivative, which contains a series of amino acids selected from SEQ ID 2-34, and combines with an Fc region of immunoglobulin through a non cucumber polymer. Claim 5: according to the composition of claim 4, it is characterized by that the non cucumber polymer is selected from the copolymers of polyethylene glycol, polypropylene glycol, ethanol and propylene glycol, poly (tetraethanol), polyvinyl alcohol, polyurethane and poly (calcium carbamate), Polyethylene ether, polypropylene propylene (polydienoic acid),Propylene (polyacrylic acid)2. Lipid polymer, thyroid, hyaluronic acid and their mixture.Una composición para prevenir o tratar la hiperlipidemia, el hígado graso o la arteriosclerosis que comprende un derivado de oxintomodulina como ingrediente activo. El derivado de oxintomodulina tiene una gran capacidad para activar el receptor de GLP-1 y el receptor de glucagón y tiene los efectos de re
