The invention is directed to topical formulations comprising plant extracts together with additional ingredients. The invention is further directed to use of the formulations in treating acne. In particular, the invention is directed to a topical formulation comprising Portulaca oleracea extract, Rheum palmatum extract, Chrysanthemum indicum extract and Scutellaria baicalensis root extract or its active ingredient Baicalin, together with nordihydroguaiaretic acid and oleanolic acid.本發明係有關包含植物萃取物，結合額外成分之局部用配方。本發明更有關該配方於治療痤瘡之用途。特別的是，本發明係有關包含馬齒莧(Portulaca oleracea)萃取物、掌葉大黃(Rheum palmatum)萃取物、油菊(Chrysanthemum indicum)萃取物與黃芩(Scutellaria baicalensis)根萃取物，或其活性成分黃芩苷(Baicalin)，以及去甲二氫癒創木酸(nordihydroguaiaretic acid)與齊墩果酸(oleanolic acid)之局部用配方。
