Formulation for topical use based on vitamin E or an ester thereof for use inremoving, reducing or inhibiting a bacterialand/ or fungal biofilm, wherein said ester of vitamin E is an ester with acarboxylic acid of formula R-COOH, in which R is an alkylradical having from 1 to 19 carbon atoms, or an alkenyl or alkynyl having from2 to 19 carbon atoms.