ISABEL, ELISE,MELLON, CHRISTOPHE,BEAULIEU, CHRISTIAN
申请号：
CA2706746
公开号：
CA2706746C
申请日:
2008.11.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Several parasitesresponsible for mammalian diseasesare dependent on cysteine proteasefor various life-cycle functions.Inhibition or decreasing functionof these proteases can be useful inthe treatment and/or prevention ofthese parasitic diseases includingtoxoplasmosis, malaria, Africantrypanosomiasis, Chagas disease,leishmaniasis, schistosomiasis,amebiasis, giardiasis, clonorchiasis,opisthorchiasis, paragonimiasis,fasciolopsiasis, lymphatic filariasis,onchocerciasis, dracunculiasis, ascariasis, trichuriasis, strongyloidiasis,trichostrongyliasis, trichomoniasis or cestodiasis.Compounds of formula I of the invention are capable of treating and/orpreventing the above-identified diseases:
