INSERM (Institut National de la Sante et de la Recherche Medicale)
发明人:
Christophe, Olivier,Denis, Cecile,Cherel, Ghislaine,Gueguen, Paul
申请号:
AU2009329493
公开号:
AU2009329493B2
申请日:
2009.12.21
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to chimeric derivatives of serine protease zymogen containing the activation peptide of factor X or a fragment thereof for improving the half- life of said derivatives. Preferably, said chimeric derivatives are protein C and factor X derivatives. The invention also relates to said derivatives for the prevention or treatment of blood coagulation disorders.