A device for elastic ligature of tissues has a first and a second element, one of which exhibits a support portion for at least a rubber ring. The elements are slidably coupled to one another such that a reciprocal sliding between the elements determines a release of a rubber ring from the support portion. A trigger is manually maneuverable by an operator and acts on the second element for realising a reciprocal sliding between the elements. A connecting portion is connected to the trigger and to the second element and is elastically deformable in order to enable a reciprocal change of orientation between the trigger and the second element.
