KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;HANDOK PHARMACEUTICALS CO., LTD.
发明人:
AHN, JIN HEE,H. S. PAGIRE,RHEE, SANG DAL,KIM, KI YOUNG,JUNG, WON HOON,BAE, MYUNG-AE,SONG, JIN SOOK,KIM, KWANG-ROK,KWAK, HYUN JUNG
申请号:
EP13781273
公开号:
EP2842938A4
申请日:
2013.04.25
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to a beta-alanine derivative, pharmaceutically acceptable salts thereof, and a pharmaceutical composition including the same as an active ingredient. The novel beta-alanine derivative and pharmaceutically acceptable salts thereof according to the present invention may effectively inhibit the activity of DGAT1, which is an enzyme serving as a catalyst in the final step of the synthesis of neutral lipids, to thereby be effectively used as a pharmaceutical composition for preventing or treating various lipid metabolism-related disorders selected from the group consisting of obesity, dyslipidemia, fatty liver, insulin resistance syndrome, and hepatitis.