DISULFIDE MASKED PRODRUG COMPOSITIONS AND METHODS

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专利权人:

MERCK SHARP & DOHME CORP.;Gabor Butora

发明人:

Gabor Butora

申请号：

US14648716

公开号：

US20150315226A1

申请日:

2013.12.02

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to disulfide masked prodrug compounds, compositions and methods that are amenable to bioactivation by a reducing agent such as glutathione. Such disulfide based compounds, compositions, and methods can be useful, for example, in providing novel prodrugs for use as therapeutics.

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