University of Washington through its Center for Commercialization
发明人:
申请号:
EP14819961.5
公开号:
EP3016683A4
申请日:
2014.07.03
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Disclosed are compositions and methods relating to antibodies that bind soluble Major Histocompatibility Complex class I chain-related (sMIC). Specifically, disclosed are antibodies designed or selected to inhibit sMIC (e.g. to neutralize sMIC) shed from MIC+ tumors. Further disclosed are methods of using the antibodies for the treatment of MIC-positive cancers.